High-throughput screening platform for CRISPR

نویسندگان

چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

High-throughput vertebrate total analysis/screening platform

...................................................................................................................................... i Acknowledgem ents .................................................................................................................... ii Table of

متن کامل

Dynamic Islet Culture Platform for High-throughput Drug Screening

Currently, we are heading towards the period of nanotechnology which extends to many engineering disciplines. The necessity of its development is crucial to make life more convenient, to improve efficiency of each research field, and to integrate portable healthcare system. Thus, the next most important step is to develop a technology to meet the needs of both industry and research area [1]. He...

متن کامل

A CRISPR CASe for high-throughput silencing

Manipulation of gene expression on a genome-wide level is one of the most important systematic tools in the post-genome era. Such manipulations have largely been enabled by expression cloning approaches using sequence-verified cDNA libraries, large-scale RNA interference libraries (shRNA or siRNA) and zinc finger nuclease technologies. More recently, the CRISPR (clustered regularly interspaced ...

متن کامل

A robust high-throughput sandwich cell-based drug screening platform.

Hepatotoxicity evaluation of pharmaceutical lead compounds in early stages of drug development has drawn increasing attention. Sandwiched hepatocytes exhibiting stable functions in culture represent a standard model for hepatotoxicity testing of drugs. We have developed a robust and high-throughput hepatotoxicity testing platform based on the sandwiched hepatocytes for drug screening. The platf...

متن کامل

Development and Optimization of High-throughput Zebrafish Screening Platform

The high-throughput zebrafish screening platform is a revolutionary tool that enables subcellular precision in vivo whole animal screening of Danio Rerio. It can perform laser surgery and/or imaging in less than twenty seconds per fish. This is a two orders of magnitude improvement from the existing manual method, which takes 10 to 15 minutes per fish. The platform also has the ability to rotat...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Materials Today

سال: 2016

ISSN: 1369-7021

DOI: 10.1016/j.mattod.2016.02.017